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"She needed so much help," he told NIH Medline Plus. Saget's sister was diagnosed at age 44, and died two years later, in 1994.
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RELATED: Bob Saget, Star of Full House and America's Funniest Home Videos, Dies at 65
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There is no direct cure for scleroderma, and instead different treatments that can target the various symptoms of the disease, such as steroid creams for the skin inflammation, blood pressure medications for any lung or kidney problems, immune suppressants and over-the-counter pain relievers. And if scleroderma reaches the digestive system, it can cause heartburn, difficulty swallowing, bloating and diarrhea. Scarring of heart tissue could lead to congestive heart failure.
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Scleroderma in the kidneys can lead to elevated blood pressure and rapid kidney failure. The lungs can develop scar tissue which can make it harder to breathe. But in severe forms, called systemic scleroderma, the disease spreads through other systems in the body and "can damage your blood vessels and internal organs, such as the heart, lungs and kidneys," according to NIH.Īnd if scleroderma spreads through the body, it affects each organ in different ways. In mild cases, scleroderma just affects the skin. The disease causes the skin to form hard, tight patches that can grow or shrink, and sometimes suddenly disappear.
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Never miss a story – sign up PEOPLE ‘s free daily newsletter to keep you updated on the best of what PEOPLE has to offer, from juicy celebrity news to compelling stories of human interest.Scleroderma is a rare, autoimmune connective tissue and rheumatic disease that primarily causes inflammation in the skin, and can lead to inflammation in other parts of the body, according to the National Institutes of Health. To date, the event has raised $ 25 million for research and treatment. He was also on the board of the Scleroderma Research Foundation and hosted the annual Cool comedy, hot kitchen fundraiser, which combined stand-up from him and his famous friends with meals prepared by top chefs.
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The severity varies, with some people seeing effects in their skin and others, in blood vessels, internal organs and the digestive tract, the Mayo Clinic shares.Īfter Gay’s death, Saget made it his mission to raise awareness and money for the disease, including creating the 1996 television movie For the hope, a story about a woman with scleroderma (played by Dana Delany) loosely based on Gay’s story.
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RELATED: How his sister’s tragic death pushed Bob Saget into a life of charitable workĪccording to the Mayo Clinic, scleroderma is “a group of rare diseases that involve hardening and tightening of the skin and connective tissue.” More prevalent in women than men, it often occurs between the ages of 30 and 50 and there is no cure. His cause of death has not yet been revealed, although no signs of drug use or unfair play were reported. That Full house actor died suddenly on January 9 – what would have been Gay’s 75th birthday. And that’s one of the things that has made me do this, will keep me doing this until I’m gone. The case added: “My sister should not be dead. I feel that to really do her justice is to really make great progress in the next decade or two and really help these sweet, innocent victims with this disease.” “For me, it’s a tribute to her and somehow telling her that her life had a real purpose,” Saget said of raising awareness about scleroderma in the interview aired Friday d. Jon LaPook on the disease and his work with the Scleroderma Research Foundation. Last month, he spoke with CBS ‘Chief Medical Correspondent Dr. In 1994, the beloved comedian lost an older sibling Gay to the autoimmune disease scleroderma. Bob Saget honored his late sister Gay in one of his last interviews before his death.